Lichen planus
https://en.wikipedia.org/wiki/Lichen_planus
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References
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis 24672362 NIH
Lichen planus (LP) mangrupikeun kaayaan radang anu berkepanjangan anu biasana mangaruhan sawawa dina umur tengahna. Éta tiasa muncul dina kulit atanapi mémbran mukosa sapertos sungut, heunceut, esophagus, kotak sora, sareng lapisan panon. LP asalna dina bentuk anu béda-béda gumantung kana kumaha rashes katingali sareng dimana munculna. Panaliti nunjukkeun yén sababaraha jinis LP, sapertos anu mangaruhan esophagus atanapi panon, panginten henteu cekap didiagnosis. Sababaraha bentuk LP, kawas tipe hypertrophic na erosive dina sungut, tiasa utamana ngabeuratkeun sarta tahan lila. Faktor séjén sapertos pangobatan atanapi kontak sareng zat-zat anu tangtu tiasa memicu ruam anu mirip.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen Planus 10865927Lichen planus mangrupikeun kaayaan kulit anu ditandaan ku nabrak wungu, datar-topped sareng patch anu tiasa nyababkeun gatal-gatal. Lesi kulit ieu tiasa ngabahayakeun, khususna nalika mangaruhan kana sungut atanapi alat kelamin parah. Dina kasus parna, oral lichen planus malah tiasa ningkatkeun résiko ngembangkeun jinis kanker kulit. Éta ogé tiasa mangaruhan kulit sirah sareng kuku. Sanaos panyababna seueur kasus teu dipikanyaho, sababaraha tiasa dipicu ku pangobatan atanapi inféksi hépatitis C. Perawatan biasana ngalibatkeun krim anu kuat pikeun kasus lokal sareng stéroid lisan pikeun anu langkung nyebar.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Oral lichen planus 32753462 NIH
Lichen planus mangrupakeun kaayaan dimana sistim imun ngabalukarkeun radang, hasilna tanda has dina kulit jeung mémbran mukosa. Mangaruhan ngeunaan 5% tina sawawa, leuwih mindeng bikang, sarta biasana dimimitian sabudeureun umur tengah. Keterlibatan lisan ditingali dina dugi ka 77% kasus, kalolobaanana mangaruhan pipi batin. Bari sababaraha urang bisa jadi teu ngarasa gejala naon, batur bisa ngalaman nyeri tur gaduh gangguan kalayan pangan tangtu (misalna asam, lada) atawa odol.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Pikeun mastikeun diagnosis lichen planus kulit, biopsi kulit tiasa dilakukeun. Immunofluoresensi langsung (DIF) tiasa mangpaat dina pasien anu lesi bullous pikeun ngabédakeun kaayaan tina panyakit vesiculobulous otoimun.